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DNA duplexes with reactive dialdehyde groups as novel reagents for cross-linking to restriction- modification enzymes.

To create new, effective reagents for affinity modification of restriction-modification (R-M) enzymes, a regioselective method for reactive dialdehyde group incorporation into oligonucleotides, based on insertion of a 1-beta-D-galactopyranosylthymine residue, has been developed. We synthesized DNA d...

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Publicat a:Nucleic Acids Res
Autors principals: Brevnov, M G, Gritsenko, O M, Mikhailov, S N, Efimtseva, E V, Ermolinsky, B S, Van Aerschot, A, Herdewijn, P, Repyk, A V, Gromova, E S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146899/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9241245/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.16.3302
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