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Cysteine 50 of the POU H domain determines the range of targets recognized by POU proteins.

The best target of POU proteins (Oct-1, Oct-2) is an octamer sequence ATGCAAAT. POU proteins also recognize, with weaker affinity, the TAAT-like targets of another group of regulatory factors, the homeoproteins. Up to now, it has not been known why Cys50 of the POUHdomain is absolutely conserved in...

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Detaylı Bibliyografya
Asıl Yazarlar: Stepchenko, A G, Luchina, N N, Pankratova, E V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC146835/
https://ncbi.nlm.nih.gov/pubmed/9207034
Etiketler: Etiketle
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