The conserved 5'-untranslated leader of Spi-1 (PU.1) mRNA is highly structured and potently inhibits translation in vitro but not in vivo.

The transcription factor Spi-1 (PU.1) has a central role in regulating myeloid gene expression during hematopoietic development and its overexpression has been implicated in erythroleukemic transformation. Thus regulation of Spi-1 expression has broad significance for hematopoietic development. A co...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Hensold, J O, Stratton, C A, Barth, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146829/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207037/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.14.2869
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