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Alteration of the Saccharomyces cerevisiae COX2 mRNA 5'-untranslated leader by mitochondrial gene replacement and functional interaction with the translational activator protein PET111.

The ability to replace wild-type mitochondrial DNA sequences in yeast with in vitro-generated mutations has been exploited to study the mechanism by which the nuclearly encoded PET111 protein specifically activates translation of the mitochondrially coded COX2 mRNA. We have generated three mutations...

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Pubblicato in:Mol Biol Cell
Autori principali: Mulero, J J, Fox, T D
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Cell Biology 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8167413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.12.1327
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