Demethylation of DNA by purified chick embryo 5-methylcytosine-DNA glycosylase requires both protein and RNA.

We have previously purified and characterized a 5-methylcytosine (5-MeC)-DNA glycosylase from 12 day old chick embryos [Jost,J.P. et al. (1995) J. Biol. Chem. 270, 9734-9739]. The activity of the purified enzyme is abolished upon treatment with proteinase K and ribonuclease A. RNA copurifies with 5-...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Frémont, M, Siegmann, M, Gaulis, S, Matthies, R, Hess, D, Jost, J P
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1997
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9171088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.12.2375
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