V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: sequence comparison reveals a putative recombinational enhancer element.
The immunoglobulin heavy chain intron enhancer (Emu) not only stimulates transcription but also V(D)J recombination of chromosomally integrated recombination substrates. We aimed at reproducing this effect in recombination competent cells by transient transfection of extrachromosomal substrates. The...
Saved in:
| Published in: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1997
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9235545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.12.2303 |
| Tags: |
No Tags, Be the first to tag this record!
|