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V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: sequence comparison reveals a putative recombinational enhancer element.

The immunoglobulin heavy chain intron enhancer (Emu) not only stimulates transcription but also V(D)J recombination of chromosomally integrated recombination substrates. We aimed at reproducing this effect in recombination competent cells by transient transfection of extrachromosomal substrates. The...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Roch, F A, Hobi, R, Berchtold, M W, Kuenzle, C C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9235545/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.12.2303
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