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Transcription factor Sp3 antagonizes activation of the ornithine decarboxylase promoter by Sp1.

Ornithine decarboxylase (ODC) expression is important for proliferation and is elevated in many tumor cells. We previously showed that Sp1 is a major positive regulator of ODC transcription. In this paper we have investigated transcriptional regulation of rat ODC by the closely related factor Sp3. W...

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Bibliographic Details
Main Authors: Kumar, A P, Butler, A P
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC146696/
https://ncbi.nlm.nih.gov/pubmed/9115370
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