Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice.

Hypermutation of immunoglobulin genes is a key process in antibody diversification. Little is known about the mechanism, but the availability of rapid facile assays for monitoring immunoglobulin hypermutation would greatly aid the development of culture systems for hypermutating B cells as well as t...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Jolly, C J, Klix, N, Neuberger, M S
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1997
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9115357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.10.1913
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