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Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice.

Hypermutation of immunoglobulin genes is a key process in antibody diversification. Little is known about the mechanism, but the availability of rapid facile assays for monitoring immunoglobulin hypermutation would greatly aid the development of culture systems for hypermutating B cells as well as t...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Jolly, C J, Klix, N, Neuberger, M S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9115357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.10.1913
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