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Investigation of the formation and intracellular stability of purine.(purine/pyrimidine) triplexes.

In a previous work we showed that a short triple helix-forming oligonucleotide (TFO) targeted to the murine c-pim-1 proto-oncogene promoter gives a very stable triple helix under physiological conditions in vitro . Moreover, this triplex was stable inside cells when preformed in vitro . However, we...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Debin, A, Malvy, C, Svinarchuk, F
Format: Artigo
Language:Inglês
Published: Oxford University Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146673/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9115364/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.10.1965
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