HIV-1 protease inhibits its homologous reverse transcriptase by protein-protein interaction.
The reading frame of the HIV-1 pol gene, encoding protease (PR) and reverse transcriptase (RT), including RNase H as well as integrase, was fused to the bacterialbeta-galactosidase gene and overexpressed in Escherichia coli cells. The resulting fusion protein was cleaved autocatalytically leading to...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146664/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.9.1709 |
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