Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans

The pathogenic fungus Cryptococcus neoformans infects humans upon inhalation and causes the most common fungal meningoencephalitis in immunocompromised subjects worldwide. In the host, C. neoformans is found both intracellularly and extracellularly, but how these two components contribute to the dev...

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Bibliographic Details
Main Authors: Rittershaus, Philipp C., Kechichian, Talar B., Allegood, Jeremy C., Merrill, Alfred H., Hennig, Mirko, Luberto, Chiara, Del Poeta, Maurizio
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1466548/
https://ncbi.nlm.nih.gov/pubmed/16741577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27890
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