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Evidence for the stochastic integration of gene trap vectors into the mouse germline.

A large scale insertional mutagenesis experiment was performed in embryonic stem (ES) cells by introducing two types of gene trap vectors into the genome. These cell lines carrying mutations were introduced into the mouse germline. In order to assess the feasibility of a large scale cloning of the t...

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Autors principals: Chowdhury, K, Bonaldo, P, Torres, M, Stoykova, A, Gruss, P
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC146629/
https://ncbi.nlm.nih.gov/pubmed/9092658
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