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Calculated distortions of duplex DNA by a cis, syn cyclobutane thymine dimer are unaffected by a 3' TpA step.

Molecular dynamics simulations were performed on the duplex DNA dodecamers d(CGCGAA TT CGCG): d(CGCGAATTCGCG) and d(GCACGAA TT AAG): d(CTTAATTCGTGC), where TT denotes a cis, syn cyclobutane thymine dimer. The constant temperature and pressure algorithm of the AMBER 4.1 molecular-modeling package was...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Cooney, M G, Miller, J H
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060440/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.7.1432
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