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Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

The role of Tyr115 of human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) in the mispair extension fidelity of DNA dependent DNA synthesis was analysed by using a series of 15 mutant enzymes with substitutions at Tyr115. Their kinetic parameters for elongation using homopolymeric RN...

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Bibliografische gegevens
Hoofdauteurs: Martín-Hernández, A M, Gutiérrez-Rivas, M, Domingo, E, Menéndez-Arias, L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC146587/
https://ncbi.nlm.nih.gov/pubmed/9060433
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