Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.

The role of Tyr115 of human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) in the mispair extension fidelity of DNA dependent DNA synthesis was analysed by using a series of 15 mutant enzymes with substitutions at Tyr115. Their kinetic parameters for elongation using homopolymeric RN...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Martín-Hernández, A M, Gutiérrez-Rivas, M, Domingo, E, Menéndez-Arias, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146587/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060433/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.7.1383
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