Augmentation of Human Immunodeficiency Virus Type 1 Subtype E (CRF01_AE) Multiple-Drug Resistance by Insertion of a Foreign 11-Amino-Acid Fragment into the Reverse Transcriptase

A human immunodeficiency virus type 1 (HIV-1) subtype E (CRF01_AE) variant (99JP-NH3-II) possessing an in-frame 33-nucleotide insertion mutation in the β3-β4 loop coding region of the reverse transcriptase (RT) gene was isolated from a patient who had not responded to nucleoside analogue RT inhibito...

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Autors principals: Sato, Hironori, Tomita, Yasuhiro, Ebisawa, Kazuyoshi, Hachiya, Atsuko, Shibamura, Kayo, Shiino, Teiichiro, Yang, Rongge, Tatsumi, Masashi, Gushi, Kazuo, Umeyama, Hideaki, Oka, Shinichi, Takebe, Yutaka, Nagai, Yoshiyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Recombination and Evolution
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114273/
https://ncbi.nlm.nih.gov/pubmed/11356968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.12.5604-5613.2001
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