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The small subunit is required for functional interaction of DNA polymerase delta with the proliferating cell nuclear antigen.

DNA polymerase delta is usually isolated as a heterodimer composed of a 125 kDa catalytic subunit and a 50 kDa small subunit of unknown function. The enzyme is distributive by itself and requires an accessory protein, the proliferating cell nuclear antigen (PCNA), for highly processive DNA synthesis...

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Udgivet i:Nucleic Acids Res
Principais autores: Zhou, J Q, He, H, Tan, C K, Downey, K M, So, A G
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146557/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9092615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.6.1094
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