The small subunit is required for functional interaction of DNA polymerase delta with the proliferating cell nuclear antigen.
DNA polymerase delta is usually isolated as a heterodimer composed of a 125 kDa catalytic subunit and a 50 kDa small subunit of unknown function. The enzyme is distributive by itself and requires an accessory protein, the proliferating cell nuclear antigen (PCNA), for highly processive DNA synthesis...
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| Pubblicato in: | Nucleic Acids Res |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1997
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9092615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.6.1094 |
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