A new method for straightening DNA molecules for optical restriction mapping.

We have developed an improved method of straightening DNA molecules for use in optical restriction mapping. The DNA was straightened on 3-aminopropyltriethoxysilane-coated glass slides using surface tension generated by a moving meniscus. In our method the meniscus motion was controlled mechanically...

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Detalhes bibliográficos
Main Authors: Yokota, H, Johnson, F, Lu, H, Robinson, R M, Belu, A M, Garrison, M D, Ratner, B D, Trask, B J, Miller, D L
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC146532/
https://ncbi.nlm.nih.gov/pubmed/9023119
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