RNase H-independent antisense activity of oligonucleotide N3 '--> P5 ' phosphoramidates.

Oligonucleotide N3'-->P5'phosphoramidates are a new and promising class of antisense agents. Here we report biological properties of phosphoramidate oligonucleotides targeted against the human T cell leukemia virus type-I Tax protein, the major transcriptional transactivator of this human retrovirus...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Autores principales:	Heidenreich, O, Gryaznov, S, Nerenberg, M
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146512/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.4.776
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