RNase H-independent antisense activity of oligonucleotide N3 '--> P5 ' phosphoramidates.

Oligonucleotide N3'-->P5'phosphoramidates are a new and promising class of antisense agents. Here we report biological properties of phosphoramidate oligonucleotides targeted against the human T cell leukemia virus type-I Tax protein, the major transcriptional transactivator of this human retrovirus...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Heidenreich, O, Gryaznov, S, Nerenberg, M
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1997
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146512/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.4.776
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