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Phosphorylation of ATF-1 enhances its DNA binding and transcription of the Na,K-ATPase alpha 1 subunit gene promoter.

Transcriptional activity of both ATF-1 and CREB is enhanced by protein phosphorylation. While enhancement has been attributed to an increase in binding affinity for a co-activator (CBP), induction of the DNA binding activity by phosphorylation is an open question. Using the Na,K-ATPase alpha1 subuni...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Kobayashi, M, Shimomura, A, Hagiwara, M, Kawakami, K
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146500/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.4.877
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