Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction

For over a century, there has been intense debate as to the reason why some cardiac stresses are pathological and others are physiological. One long-standing theory is that physiological overloads such as exercise are intermittent, while pathological overloads such as hypertension are chronic. In th...

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Bibliographic Details
Main Authors: Perrino, Cinzia, Prasad, Sathyamangla V. Naga, Mao, Lan, Noma, Takahisa, Yan, Zhen, Kim, Hyung-Suk, Smithies, Oliver, Rockman, Howard A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2006
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464895/
https://ncbi.nlm.nih.gov/pubmed/16741575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25397
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