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Cryptic splice site usage in exon 7 of the human fibrinogen Bβ-chain gene is regulated by a naturally silent SF2/ASF binding site within this exon
In this work we report the identification of a strong SF2/ASF binding site within exon 7 of the human fibrinogen Bβ-chain gene (FGB). Its disruption in the wild-type context has no effect on exon recognition. However, when the mutation IVS7 + 1G>T—initially described in a patient suffering from c...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464855/ https://ncbi.nlm.nih.gov/pubmed/16611940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2269306 |
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