CELLULAR AND SUBCELLULAR LOCALIZATION OF PDE10A, A STRIATUM-ENRICHED PHOSPHODIESTERASE

PDE10A is a recently identified phosphodiesterase that is highly expressed by the GABAergic medium spiny projection neurons of the mammalian striatum. Inhibition of PDE10A results in striatal activation and behavioral suppression, suggesting that PDE10A inhibitors represent a novel class of antipsyc...

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Autors principals: XIE, Z., ADAMOWICZ, W. O., ELDRED, W. D., JAKOWSKI, A. B., KLEIMAN, R. J., MORTON, D. G., STEPHENSON, D. T., STRICK, C. A., WILLIAMS, R. D., MENNITI, F. S.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464838/
https://ncbi.nlm.nih.gov/pubmed/16483723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2005.12.042
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