Kv7/KCNQ/M and HCN/h, but not K(Ca)2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells

In hippocampal pyramidal cells, a single action potential (AP) or a burst of APs is followed by a medium afterhyperpolarization (mAHP, lasting ∼0.1 s). The currents underlying the mAHP are considered to regulate excitability and cause early spike frequency adaptation, thus dampening the response to...

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Bibliographic Details
Main Authors: Gu, Ning, Vervaeke, Koen, Hu, Hua, Storm, Johan F
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
Subjects:
Cell Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464792/
https://ncbi.nlm.nih.gov/pubmed/15890705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.086835
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