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The synthesis and stability of oligodeoxyribonucleotides containing the deoxyadenosine mimic 1-(2'-deoxy-beta-D-ribofuranosyl)imidazole-4-carboxamide.

Oligodeoxyribonucleotides containing the nucleoside analog 1-(2'-deoxy-beta-D-ribofuranosyl) imidazole-4-carboxamide (1) were synthesized by solid phase phosphoramidite technology. Nucleoside 1, which contains a reactive exocyclic amide moiety, was incorporated into synthetic oligodeoxyribonucleotid...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Johnson, W T, Zhang, P, Bergstrom, D E
Format: Artigo
Language:Inglês
Published: Oxford University Press 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016596/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.3.559
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