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Effect of the 1-(2'-deoxy-beta-D-ribofuranosyl)-3-nitropyrrole residue on the stability of DNA duplexes and triplexes.

3-Nitropyrrole (M) was introduced as a non-discriminating 'universal' base in nucleic acid duplexes by virtue of small size and a presumed tendency to stack but not hydrogen bond with canonical bases. However, the absence of thermally-induced hyperchromic changes by single-stranded deoxyoligomers in...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Amosova, O, George, J, Fresco, J R
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9115359/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.10.1930
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