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A critical role for the Calcium-promoted Ras Inactivator in Fcγ receptor-mediated phagocytosis

Fc receptor (FcR)-mediated phagocytosis requires activation of the Rho GTPases Cdc42 and Rac1, but how they are recruited to the FcR is unknown. Here we show that the Ca(2+)-promoted Ras inactivator (CAPRI), a Ras GTPase-activating protein, functions as an adaptor for Cdc42 and Rac1 during FcR-media...

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Bibliografske podrobnosti
Main Authors: Zhang, Jun, Guo, Jian, Dzhagalov, Ivan, He, You-Wen
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464573/
https://ncbi.nlm.nih.gov/pubmed/16041389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1232
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