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A critical role for the Calcium-promoted Ras Inactivator in Fcγ receptor-mediated phagocytosis
Fc receptor (FcR)-mediated phagocytosis requires activation of the Rho GTPases Cdc42 and Rac1, but how they are recruited to the FcR is unknown. Here we show that the Ca(2+)-promoted Ras inactivator (CAPRI), a Ras GTPase-activating protein, functions as an adaptor for Cdc42 and Rac1 during FcR-media...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464573/ https://ncbi.nlm.nih.gov/pubmed/16041389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1232 |
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