Potassium-resistant triple helix formation and improved intracellular gene targeting by oligodeoxyribonucleotides containing 7-deazaxanthine.

Triple helix formation by purine-rich oligonucleotides in the anti-parallel motif is inhibited by physiological concentrations of potassium. Substitution with 7-deazaxanthine (c7X) has been suggested as a strategy to overcome this effect. We have tested this by examining triple helix formation both...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Faruqi, A F, Krawczyk, S H, Matteucci, M D, Glazer, P M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1997
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016606/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.3.633
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