Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation

In the present study, our aim was to determine whether intrafetal glucose infusion increases fetal adiposity, synthesis and secretion of leptin and regulates gene expression of the ‘appetite regulatory’ neuropeptides neuropepetide Y (NPY), agouti-related peptide (AGRP), pro-opiomelanocortin (POMC) a...

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Bibliographic Details
Main Authors: Mühlhäusler, BS, Adam, CL, Marrocco, EM, Findlay, PA, Roberts, CT, McFarlane, JR, Kauter, KG, McMillen, IC
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
Subjects:
Developmental Programming
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464501/
https://ncbi.nlm.nih.gov/pubmed/15661821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.079079
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