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Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation

In the present study, our aim was to determine whether intrafetal glucose infusion increases fetal adiposity, synthesis and secretion of leptin and regulates gene expression of the ‘appetite regulatory’ neuropeptides neuropepetide Y (NPY), agouti-related peptide (AGRP), pro-opiomelanocortin (POMC) a...

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Autors principals: Mühlhäusler, BS, Adam, CL, Marrocco, EM, Findlay, PA, Roberts, CT, McFarlane, JR, Kauter, KG, McMillen, IC
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464501/
https://ncbi.nlm.nih.gov/pubmed/15661821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.079079
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