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Hyperalgesia induced by cutaneous freeze injury for testing analgesics in healthy volunteers

AIMS: The early phases of the clinical development of new analgesic agents are severely hindered by a lack of reliable sensitive tests based on experimental pain models. The aim of this study was to assess the ability of a localized hyperalgesia model induced by cutaneous freeze injury to evaluate t...

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Detalles Bibliográficos
Main Authors: Chassaing, Claude, Schmidt, Jeannot, Eschalier, Alain, Cardot, Jean Michel, Dubray, Claude
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464424/
https://ncbi.nlm.nih.gov/pubmed/16542199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02582.x
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