Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats

1. Magnesium (Mg)-deficient rats develop a mechanical hyperalgesia which is reversed by a N-Methyl-D-Aspartate (NMDA) receptor antagonist. Given that functioning of this receptor-channel is modulated by Mg, we wondered whether facilitated activation of NMDA receptors in Mg deficiency state may in tu...

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Détails bibliographiques
Auteurs principaux: Begon, Sophie, Pickering, Gisèle, Eschalier, Alain, Mazur, André, Rayssiguier, Yves, Dubray, Claude
Format: Artigo
Langue:Inglês
Publié: 2001
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Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573046/
https://ncbi.nlm.nih.gov/pubmed/11704642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704354
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