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Binding site of the M-domain of human protein SRP54 determined by systematic site-directed mutagenesis of signal recognition particle RNA.

The interaction of protein SRP54M from the human signal recognition particle with SRP RNA was studied by systematic site-directed mutagenesis of the RNA molecule. Protein binding sites were identified by the analysis of mutations that removed individual SRP RNA helices or disrupted helical sections...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Gowda, K, Chittenden, K, Zwieb, C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.2.388
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