The SV40 large T-antigen helicase can unwind four stranded DNA structures linked by G-quartets.

We describe a novel activity of the SV40 large T-ag helicase, the unwinding of four stranded DNA structures linked by stacked G-quartets, namely stacked groups of four guanine bases bound by Hoogsteen hydrogen bonds. The structures unwound by the helicase were of two types: (i) quadruplexes comprisi...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Baran, N, Pucshansky, L, Marco, Y, Benjamin, S, Manor, H
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1997
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146434/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016557/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.2.297
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