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Microfabricated bioprocessor for integrated nanoliter-scale Sanger DNA sequencing

An efficient, nanoliter-scale microfabricated bioprocessor integrating all three Sanger sequencing steps, thermal cycling, sample purification, and capillary electrophoresis, has been developed and evaluated. Hybrid glass–polydimethylsiloxane (PDMS) wafer-scale construction is used to combine 250-nl...

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Détails bibliographiques
Auteurs principaux: Blazej, Robert G., Kumaresan, Palani, Mathies, Richard A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464327/
https://ncbi.nlm.nih.gov/pubmed/16648246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602476103
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