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Integrated microfluidic bioprocessor for single-cell gene expression analysis

An integrated microdevice is developed for the analysis of gene expression in single cells. The system captures a single cell, transcribes and amplifies the mRNA, and quantitatively analyzes the products of interest. The key components of the microdevice include integrated nanoliter metering pumps,...

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Bibliografiske detaljer
Main Authors: Toriello, Nicholas M., Douglas, Erik S., Thaitrong, Numrin, Hsiao, Sonny C., Francis, Matthew B., Bertozzi, Carolyn R., Mathies, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629289/
https://ncbi.nlm.nih.gov/pubmed/19075237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806355106
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