Effects of variations in length of hammerhead ribozyme antisense arms upon the cleavage of longer RNA substrates.
The efficacy of intracellular binding of hammerhead ribozyme to its cleavage site in target RNA is a major requirement for its use as a therapeutic agent. Such efficacy can be influenced by several factors, such as the length of the ribozyme antisense arms and mRNA secondary structures. Analysis of...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1997
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146427/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.2.333 |
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