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Effects of variations in length of hammerhead ribozyme antisense arms upon the cleavage of longer RNA substrates.

The efficacy of intracellular binding of hammerhead ribozyme to its cleavage site in target RNA is a major requirement for its use as a therapeutic agent. Such efficacy can be influenced by several factors, such as the length of the ribozyme antisense arms and mRNA secondary structures. Analysis of...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
第一著者: Sioud, M
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016562/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.2.333
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