Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the K(ATP) channel in the rat

This study was conducted to examine the role of myocardial ATP-sensitive potassium (K(ATP)) channels in exercise-induced protection from ischaemia–reperfusion (I–R) injury. Female rats were either sedentary (Sed) or exercised for 12 weeks (Tr). Hearts were excised and underwent a 1–2 h regional I–R...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Brown, David A, Chicco, Adam J, Jew, Korinne N, Johnson, Micah S, Lynch, Joshua M, Watson, Peter A, Moore, Russell L
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2005
Sujets:
Tissue, System and Organ Physiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464258/
https://ncbi.nlm.nih.gov/pubmed/16223762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.095729
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