Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the K(ATP) channel in the rat

This study was conducted to examine the role of myocardial ATP-sensitive potassium (K(ATP)) channels in exercise-induced protection from ischaemia–reperfusion (I–R) injury. Female rats were either sedentary (Sed) or exercised for 12 weeks (Tr). Hearts were excised and underwent a 1–2 h regional I–R...

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Detalhes bibliográficos
Main Authors: Brown, David A, Chicco, Adam J, Jew, Korinne N, Johnson, Micah S, Lynch, Joshua M, Watson, Peter A, Moore, Russell L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Tissue, System and Organ Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464258/
https://ncbi.nlm.nih.gov/pubmed/16223762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.095729
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