Distamycin prolongs E-selectin expression by interacting with a specific NF-kappaB-HMG-I(Y) binding site in the promoter.

The E-selectin cell adhesion protein plays a critical role in mediating adherence of leukocytes to endothelium at sites of inflammation. Cytokine-induced E-selectin expression on the surface of endothelial cells is transient; mRNA expression peaks at 3-4 h after induction and returns to basal levels...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Ghersa, P, Whelan, J, Cambet, Y, DeLamarter, J F, Hooft van Huijsduijnen, R
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146425/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.2.339
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