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IP(3)-mediated Ca(2+) increases do not involve the ryanodine receptor, but ryanodine receptor antagonists reduce IP(3)-mediated Ca(2+) increases in guinea-pig colonic smooth muscle cells
Smooth muscle responds to IP(3)-generating (sarcolemma acting) neurotransmitters and hormones by releasing Ca(2+) from the sarcoplasmic reticulum (SR) via IP(3) receptors (IP(3)Rs). This release may propagate as Ca(2+) waves. The Ca(2+) signal emanating from IP(3) generation may be amplified by its...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464235/ https://ncbi.nlm.nih.gov/pubmed/16195318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.096529 |
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