Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells

Reports differ as to whether reconstitution of telomerase activity alone is sufficient for immortalization of different types of human somatic cells or whether additional activities encoded by other “immortalizing” genes are also required. Here we show that ectopic expression of either the catalytic...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	O'Hare, Michael J., Bond, Jacquelyn, Clarke, Catherine, Takeuchi, Yasuhiro, Atherton, Amanda J., Berry, Catherine, Moody, John, Silver, Andrew R. J., Davies, Derek C., Alsop, Amber E., Neville, A. Munro, Jat, Parmjit S.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2001
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11209060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.2.646
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