Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

Human telomeric DNA consists of tandem repeats of the sequence d(TTAGGG). The formation and stabilization of DNA G-quadruplexes in the human telomeric sequence have been shown to inhibit the activity of telomerase, thus the telomeric DNA G-quadruplex has been considered as an attractive target for c...

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Bibliographic Details
Main Authors: Ambrus, Attila, Chen, Ding, Dai, Jixun, Bialis, Tiffanie, Jones, Roger A., Yang, Danzhou
Format: Artigo
Language:Inglês
Published: Oxford University Press 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464114/
https://ncbi.nlm.nih.gov/pubmed/16714449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl348
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