Pharmacokinetics of primaquine in man. II. Comparison of acute vs chronic dosage in Thai subjects.

We have investigated the pharmacokinetics of primaquine after acute and chronic administration of the drug to five healthy Thai volunteers. After acute dosage (15 mg p.o.) mean (+/- s.d.) peak plasma concentrations of 65.0 +/- 34.7 ng ml-1 were achieved within 2 +/- 1h. Thereafter plasma drug concen...

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Detalhes bibliográficos
Main Authors: Ward, S A, Mihaly, G W, Edwards, G, Looareesuwan, S, Phillips, R E, Chanthavanich, P, Warrell, D A, Orme, M L, Breckenridge, A M
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463877/
https://ncbi.nlm.nih.gov/pubmed/4027118
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