Investigation of drug absorption from the gastrointestinal tract of man: III. Metoprolol in the colon

1 The colonic absorption of metoprolol was indirectly evaluated by measuring drug appearance in plasma following intravenous, jejunal or colonic infusion in six healthy volunteers. Plasma concentrations of α-hydroxymetoprolol and urinary excretion of the main metabolites were also measured. 2 Plasma...

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Main Authors: Godbillon, J., Evard, D., Vidon, N., Duval, M., Schoeller, J. P., Bernier, J. J., Hirtz, J.
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Basic Absorption Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463759/
https://ncbi.nlm.nih.gov/pubmed/4005112
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