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Investigation of drug absorption from the gastrointestinal tract of man: III. Metoprolol in the colon
1 The colonic absorption of metoprolol was indirectly evaluated by measuring drug appearance in plasma following intravenous, jejunal or colonic infusion in six healthy volunteers. Plasma concentrations of α-hydroxymetoprolol and urinary excretion of the main metabolites were also measured. 2 Plasma...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1985
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1463759/ https://ncbi.nlm.nih.gov/pubmed/4005112 |
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