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Influence of chronic dosing on theophylline clearance.

Theophylline clearance was studied in normal healthy volunteers before and after chronic oral dosing. Oral theophylline clearance showed a significant decrease (P less than 0.001) from 59.3 +/- 6.48 ml/min (mean +/- s.e. mean, n = 10) to 48.0 +/- 6.4 ml/min. Steady-state intravenous clearance decrea...

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Detalhes bibliográficos
Main Authors: Efthimiou, H, Morgan, D J, Ioannides-Demos, L, Raymond, K, McLean, A J
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463460/
https://ncbi.nlm.nih.gov/pubmed/6733000
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